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tetanus prophylaxis

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댓글 0건 조회 2,318회 작성일 20-04-27 09:42

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Wound management and tetanus prophylaxis
Previous doses of tetanus toxoid*Clean and minor woundAll other wounds
Tetanus toxoid-containing vaccineΔHuman tetanus immune globulinTetanus toxoid-containing vaccineΔHuman tetanus immune globulin◊
<3 doses or unknownYes§NoYes§Yes
≥3 dosesOnly if last dose given ≥10 years agoNoOnly if last dose given ≥5 years ago¥No
Appropriate tetanus prophylaxis should be administered as soon as possible following a wound but should be given even to patients who present late for medical attention. This is because the incubation period is quite variable; most cases occur within 8 days, but the incubation period can be as short as 3 days or as long as 21 days. For patients who have been vaccinated against tetanus previously but who are not up to date, there is likely to be little benefit in administering human tetanus immune globulin more than 1 week or so after the injury. However, for patients thought to be completely unvaccinated, human tetanus immune globulin should be given up to 21 days following the injury; Td or Tdap should be given concurrently to such patients.

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